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longevity TrendingFDA Approved

Omega-3 Fatty Acids (EPA/DHA)

Also known as: Fish Oil, EPA, DHA, Omega-3

Anti-inflammatory foundation — cardiovascular, cognitive, and skin health

Method

oral

Level

beginner

Risk

moderate

Status

FDA Approved

Quick Summary

Anti-inflammatory foundation — cardiovascular, cognitive, and skin health

Also called: Fish Oil, EPA, DHA, Omega-3

What is Omega-3 Fatty Acids (EPA/DHA)?

Omega-3 fatty acids (EPA and DHA) are essential polyunsaturated fats with the most extensive evidence base of any supplement. EPA reduces systemic inflammation via prostaglandin and leukotriene modulation. DHA is a structural component of neuronal membranes and the retina. Combined, they reduce triglycerides, lower cardiovascular risk, support cognitive function, improve skin barrier function, and reduce inflammatory skin conditions. The REDUCE-IT trial demonstrated 25% reduction in cardiovascular events with high-dose EPA (Bhatt et al., 2019).

How It's Made

EPA and DHA are derived from marine sources (fish oil, krill oil, algae oil). Triglyceride form has superior bioavailability to ethyl ester form. Algae-derived omega-3 is suitable for vegans.

Potential Benefits

Cardiovascular risk reduction
Anti-inflammatory effects
Cognitive support and neuroprotection
Skin barrier improvement
Triglyceride reduction
Mood support
Joint inflammation reduction

Who Uses This?

Common goals and use cases for Omega-3 Fatty Acids (EPA/DHA):

Cardiovascular healthAnti-aging protocolCognitive performanceSkin healthAthletic recoveryGeneral health foundation

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