Educational Content Only: Not medical advice. Always consult a qualified healthcare provider before using any compounds. Many peptides are research chemicals not approved by the FDA.
Quick Summary
The most versatile skincare active — brightening, barrier repair, and pore minimization
Also called: Nicotinamide, Vitamin B3, Niacin amide
What is Niacinamide?
Niacinamide (vitamin B3) is one of the most well-researched and well-tolerated skincare actives available OTC. It addresses multiple skin concerns simultaneously: reduces hyperpigmentation by inhibiting melanosome transfer, strengthens the skin barrier by increasing ceramide synthesis, minimizes pore appearance, reduces sebum production, and has anti-inflammatory properties. Pairs exceptionally well with Tretinoin to counteract irritation and with Vitamin C for synergistic brightening.
How It's Made
Niacinamide is the amide form of niacin (vitamin B3), produced through chemical synthesis or fermentation. Widely available in concentrations of 5–20% in serums and moisturizers.
Potential Benefits
Who Uses This?
Common goals and use cases for Niacinamide: