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MOTS-c

Also known as: Mitochondrial Open Reading Frame of the 12S rRNA-c

Mitochondrial peptide — metabolic regulation and longevity

Method

injection

Level

advanced

Risk

moderate

Status

Research Only

Quick Summary

Mitochondrial peptide — metabolic regulation and longevity

Also called: Mitochondrial Open Reading Frame of the 12S rRNA-c

What is MOTS-c?

MOTS-c is a mitochondria-derived peptide encoded within the mitochondrial genome (12S rRNA region). It is one of a new class of 'mitokines' — signaling molecules produced by mitochondria that regulate systemic metabolism. Research has demonstrated its role in insulin sensitivity, exercise performance, metabolic homeostasis, and aging.

How It's Made

MOTS-c is a 16-amino acid peptide encoded in the mitochondrial genome. For research and supplementation purposes, it is produced via solid-phase peptide synthesis. It is available as a lyophilized powder for injection.

Potential Benefits

Improved insulin sensitivity
Enhanced exercise performance
Metabolic regulation
Potential longevity effects
Reduced age-related metabolic decline
Anti-obesity effects

Who Uses This?

Common goals and use cases for MOTS-c:

Metabolic health optimizationExercise performanceAnti-aging protocolsInsulin resistanceLongevity medicine

Where to Buy MOTS-c

Affiliate links — use code for discount. Always consult a healthcare provider before use.

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