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GHK-Cu

Also known as: Copper Peptide GHK, Copper Tripeptide-1

The skin remodeling peptide — collagen, elastin, and wound healing

Method

topical

Level

beginner

Risk

moderate

Status

Research Only

Quick Summary

The skin remodeling peptide — collagen, elastin, and wound healing

Also called: Copper Peptide GHK, Copper Tripeptide-1

What is GHK-Cu?

GHK-Cu (Glycyl-L-Histidyl-L-Lysine copper complex) is a naturally occurring copper peptide found in human plasma, saliva, and urine. It is one of the most extensively researched peptides in skincare and anti-aging medicine. GHK-Cu levels decline significantly with age — from approximately 200 ng/mL at age 20 to 80 ng/mL by age 60 — correlating with the visible signs of skin aging.

How It's Made

GHK-Cu is a naturally occurring tripeptide that forms a complex with copper ions (Cu2+). For commercial use, it is synthesized via solid-phase peptide synthesis and then complexed with copper. It is available in topical formulations (serums, creams) and as an injectable.

Potential Benefits

Stimulates collagen and elastin production
Reduces fine lines and wrinkles
Improves skin firmness and elasticity
Accelerates wound healing
Reduces hyperpigmentation
Promotes hair growth
Anti-inflammatory effects
Antioxidant protection

Who Uses This?

Common goals and use cases for GHK-Cu:

Anti-aging skincareWound healingHair loss treatmentPost-procedure skin recoveryHyperpigmentationSkin texture improvement

Where to Buy GHK-Cu

Affiliate links — use code for discount. Always consult a healthcare provider before use.

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